Twenty four-time Grand Slam champion Novak Djokovic will face world number two Carlos Alcaraz in the US Open 2025 men's singles semi-final. The duo have faced each other eight times in the men's singles event, with Djokovic winning five matches and Alcaraz emerging victorious in three. Notably, Alcaraz last defeated Djokovic in the final of Wimbledon 2024.