Indigestion is usually harmless, but symptoms like ongoing bloating, unexplained weight loss, or difficulty swallowing may point to serious issues. Dr Shankar Zanwar, Senior Consultant Gastroenterologist at Gleneagles Hospitals, Parel, Mumbai, warned that such signs could signal conditions like GERD, ulcers, or cancer. Timely diagnosis with tests like endoscopy or scans can be life-saving.